New pill could reduce CTE in Washington patients

Research done on mice with concussions could ultimately lead to a treatment for humans who are suffering from chronic traumatic encephalopathy. CTE is a progressive disease that is often seen in boxers or football players who routinely take blows to the head. By simulating mild and severe concussions in mice, scientists realized that CTE is caused by tangles in a brain protein called tau.

At first, they were not sure how these tangles occur. However, they believe that the tangles may begin as irregularly shaped tau proteins that may be eliminated with an antibody. The antibody would bind to the irregular protein and let the body know that it is an unneeded protein that should be cleared away. The findings may present a pathway to creating a drug that could help those who have CTE.

Scientists involved in the say that the next step is to humanize the mouse antibody, which could be done in the next couple of years. If successful, a new drug could stop CTE or brain damage after a major brain injury or even help to prevent Alzheimer’s Disease. Funding for the project was provided by the National Football League Players Association, the National Institutes of Health and the Alzheimer’s Association.

Those who have suffered from a serious brain injury caused by the negligent act of another, such as in a slip-and-fall accident, may wish to consult with a personal injury attorney to determine the recourse that may be available. After a review of the available evidence, legal counsel may recommend the filing of a lawsuit against the responsible party seeking the recovery of damages for the losses that have been incurred.